Blood Markers of Inflammation, Neurodegeneration, and Cardiovascular Risk in Early Parkinson's Disease.
Michael BartlMohammed DaknaSebastian SchadeBirgit OtteTamara WickeElisabeth LangMaritta StarkeJens EbentheuerSandrina WeberKarl ToischerMoritz SchnelleFriederike Sixel-DöringClaudia TrenkwalderBrit MollenhauerPublished in: Movement disorders : official journal of the Movement Disorder Society (2022)
We identified and validated possible PD plasma biomarker candidates for state, fate, and disease progression, elucidating new molecular processes with reduced endothelial/atherosclerotic processes, increased thromboembolic risk, and neuroinflammation. Further investigations and validation in independent and larger longitudinal cohorts are needed. © 2022 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.