Evaluating UK National Guidance for Screening of Children for Tuberculosis. A Prospective Multicenter Study.
Beate KampmannJames A SeddonJames PatonZohreh NademiDenis KeaneBhanu WilliamsAmanda WilliamsSue LiebeschutzAnna RiddellJolanta BernatonieneSanjay PatelNuria MartinezPaddy McMasterRobindra Basu-RoySteven B WelchPublished in: American journal of respiratory and critical care medicine (2019)
In this low-prevalence setting we saw no incident cases of TB disease in children who were TST-positive but IGRA-negative and did not receive treatment for TB infection. Following the latest NICE guidance, significantly more children will require medication.