Clinical long-term nocturnal sleeping disturbances and excessive daytime sleepiness in Parkinson's disease.
Rocío Del PinoAne Murueta-GoyenaUnai AyalaMarian AceraMónica FernándezBeatriz TijeroMar CarmonaTamara FernándezIñigo GabilondoJuan Carlos Gómez-EstebanPublished in: PloS one (2021)
Sleep disturbances changed over time and age, diseases duration, motor impairment, treatment and sex were associated with nocturnal sleep problems and EDS. Agonist treatment alone or in combination with L-dopa might predict worse daytime sleepiness, while L-dopa in monotherapy is related to lower EDS, which significantly affects the quality of life of PD patients.
Keyphrases
- sleep quality
- obstructive sleep apnea
- sleep apnea
- depressive symptoms
- end stage renal disease
- positive airway pressure
- physical activity
- blood pressure
- chronic kidney disease
- ejection fraction
- randomized controlled trial
- prognostic factors
- body mass index
- clinical trial
- peritoneal dialysis
- study protocol
- patient reported