Genetically predicted frailty index and risk of stroke and Alzheimer's disease.

Weishi LiuLuyang ZhangHui FangYuan GaoKai LiuShen LiHongbing LiuXin WangChen LiuBo SongZongping XiaYu-Ming Xu

Published in: European journal of neurology (2022)

The MR study suggested that genetically predicted FI may be associated with an increased risk of any stroke. Subgroup analysis indicated a suggestive association between genetically predicted FI and the risk of LAS. The underlying mechanisms need further investigation.

Keyphrases

atrial fibrillation
cognitive decline
magnetic resonance
randomized controlled trial
clinical trial
phase iii
brain injury
study protocol
open label