Amanitin intoxication: effects of therapies on clinical outcomes - a review of 40 years of reported cases.
Jia Lin TanJanine StamAad P van den BergPatrick Ferry van RheenenBart G J DekkersDaniel J TouwPublished in: Clinical toxicology (Philadelphia, Pa.) (2022)
Based on data available, no statistical differences could be observed for the effects of NAC, PEN or SIL in proven poisonings with amanitin-containing mushrooms. However, monotherapy with SIL or PEN and combination therapy with NAC/SIL appear to be associated with higher survival rates compared to supportive care alone. AST, ALT, TSB, and INR values are possible predictors of potentially fatal outcomes.