Acute Effects of Metformin and Vildagliptin after a Lipid-Rich Meal on Postprandial Microvascular Reactivity in Patients with Type 2 Diabetes and Obesity: A Randomized Trial.
Alessandra SchiappacassaPriscila Alves MaranhãoMaria das Graças Coelho de SouzaDiogo G PanazzoloJosé Firmino Nogueira NetoEliete BouskelaLuiz Guilherme Kraemer-AguiarPublished in: Journal of clinical medicine (2020)
After the intake of a lipid-rich meal, the use of vildagliptin preserved postprandial non-nutritive microflow and vasomotion, while metformin increased capillary recruitment, suggesting protective and different mechanisms of action on microcirculation.