Network Pharmacology-Based Strategy for Predicting Active Ingredients and Potential Targets of Coptis chinensis Franchin Polycystic Ovary Syndrome.

Jian Xiong Ma Miao-Yong Ye Ke Ma Kang Zhou Yingying Zhang Xi-Ting Wang Hongxuan Tong

Published in: Evidence-based complementary and alternative medicine : eCAM (2021)

This preliminary study verified the basic pharmacological effects and mechanisms of C. chinensis, a TCM, in the treatment of PCOS. These results indicate that the therapeutic effects of C. chinensis on PCOS may be achieved by regulating the expression of inflammatory factors. This study provides new insights for the systematic exploration of the mechanism of traditional Chinese medicine.

Keyphrases

polycystic ovary syndrome
insulin resistance
poor prognosis
oxidative stress
type diabetes
metabolic syndrome
adipose tissue
risk assessment
replacement therapy