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Initial Treatment Response in Ocular Myasthenia Gravis: A Comparison Between Low and Moderate Doses of Prednisolone.

Thanatporn ThreetongAnuchit PoonyathalangPisit PreechawatPanitha JindahraTanyatuth PadungkiatsagulKavin Vanikieti
Published in: Clinical ophthalmology (Auckland, N.Z.) (2020)
Treatment of OMG with an average 12-week cumulative dose of prednisolone <0.435 mg/kg/day (low dose) shows a comparable responsive outcome to 0.435-1.000 mg/kg/day of prednisolone (moderate dose). Treating OMG with low-dose prednisolone can minimize prednisolone-related adverse events. However, a prospective randomized controlled trial with a larger study population is warranted in order to gain more insight into the proper dosage of prednisolone for OMG.
Keyphrases
  • low dose
  • randomized controlled trial
  • myasthenia gravis
  • high dose
  • high intensity
  • study protocol
  • clinical trial
  • systematic review
  • cancer therapy
  • replacement therapy
  • combination therapy
  • placebo controlled