Utility of the 2018 revised ISN/RPS thresholds for glomerular crescents in childhood-onset lupus nephritis: a Pediatric Nephrology Research Consortium study.
Pooja PatelMarietta de GuzmanM John HicksJoseph G MaliakkalMichelle N RheaultDavid T SelewskiKatherine TwombleyJason M MisuracCheryl L TranAlexandru R ConstantinescuAli M OnderMeredith SeamonWacharee SeeherunvongVaishali SinghCynthia PanDaryl M OkamuraAbiodun OmolojaMahmoud KallashWilliam E SmoyerGuillermo HidalgoScott E WenderferPublished in: Pediatric nephrology (Berlin, Germany) (2022)
In children with crescentic LN, use of 10% and 25% thresholds for cellular crescents better reflects disease activity, while these thresholds for fibrous crescents better discriminates kidney disease outcomes. A higher resolution version of the Graphical abstract is available as Supplementary information.
Keyphrases
- disease activity
- systemic lupus erythematosus
- rheumatoid arthritis
- rheumatoid arthritis patients
- ankylosing spondylitis
- young adults
- juvenile idiopathic arthritis
- type diabetes
- healthcare
- health information
- childhood cancer
- psychometric properties
- skeletal muscle
- weight loss
- high glucose
- glycemic control
- insulin resistance