Overexpression of Stathmin 1 Predicts Poor Prognosis and Promotes Cancer Cell Proliferation and Migration in Ovarian Cancer.

Lekai NieChen ZhangHaiyun SongQianqian ZhaoLei ChengPei-Hai Zhang Xingsheng Yang

Published in: Disease markers (2022)

STMN1 is overexpressed in ovarian cancer, and its high expression suggests a poor prognosis. STMN1 promotes the proliferation and migration of ovarian cancer and is regulated by E2F1. Thus, STMN1 may serve as a negative prognostic factor and possible target for the treatment of ovarian cancer patients.

Keyphrases

poor prognosis
long non coding rna
prognostic factors
cell proliferation
transcription factor