Regional Citrate Anticoagulation for Continuous Renal Replacement Therapy - A Safe and Effective Low-Dose Protocol.

Cheng Boon PohPoh Choo TanJia Wen KamChuin SiauNoelle L LimWenxiang YeonHai Hua CuiHai Ting DingXiao Ying SongPeng YanKai Li CheaJin Shu LiuChang Yin Chionh

Published in: Nephrology (Carlton, Vic.) (2019)

The RCA protocol with a lower initial citrate dose of 2.5 mmol/L blood had less citrate-related complications with no loss of efficacy. A more precise RCA prescription at the start of treatment avoids unnecessary citrate exposure and improves safety.

Keyphrases

low dose
randomized controlled trial
acute kidney injury
atrial fibrillation
venous thromboembolism
risk factors
combination therapy
drug induced