Effects of the combination of atomoxetine and oxybutynin in Japanese patients with obstructive sleep apnoea: A randomized controlled crossover trial.
Toru KinouchiJiro TeradaSeiichiro SakaoKen KoshikawaTsuyoshi SasakiAtsuhiko SugiyamaShun SatoNoriko SakumaMitsuhiro AbeKohei ShikanoNami HayamaYuki ShikoYoshihito OzawaShinobu IkedaTakuji SuzukiKoichiro TatsumiPublished in: Respirology (Carlton, Vic.) (2022)
Overall, ATO-OXY therapy does not reduce AHI in Japanese OSA patients, although AHI was decreased in a proportion of patients. Future studies for identifying treatment response group characteristics are warranted.