Effect of supplemental nutrition in pregnancy on offspring's risk of cardiovascular disease in young adulthood: Long-term follow-up of a cluster trial from India.
Sanjay KinraJohn GregsonPoornima PrabhakaranVipin GuptaGagandeep Kaur WaliaSanthi BhogadiRuby GuptaAastha AggarwalPoppy Alice Carson MallinsonBharati KulkarniDorairaj PrabhakaranGeorge Davey SmithK V Radha KrishnaShah EbrahimHannah KupperYoav Ben-ShlomoPublished in: PLoS medicine (2020)
Our results showed that in an area with prevalent undernutrition, protein-calorie food supplements offered to pregnant women and their offspring below the age of 6 years were not associated with lower levels of cardiovascular risk factors among offspring when they were young adults. Our findings, coupled with evidence from other intervention studies to date, suggest that policy makers should attach limited value to cardiovascular health benefits of maternal and child protein-calorie food supplementation programmes.
Keyphrases
- cardiovascular risk factors
- cardiovascular disease
- high fat diet
- pregnant women
- young adults
- pregnancy outcomes
- mental health
- randomized controlled trial
- weight loss
- healthcare
- metabolic syndrome
- protein protein
- study protocol
- public health
- binding protein
- amino acid
- human health
- type diabetes
- depressive symptoms
- preterm birth
- adipose tissue
- small molecule
- phase ii
- middle aged
- skeletal muscle
- climate change