Laboratory parameters and outcomes in hospitalized adults with COVID-19: a scoping review.
Andrew ZhuGeorge ZakusiloMatthew S LeeJulie KimHyejin KimXiaohan YingYu Han ChenCaroline JedlickaKeith MagesJustin J ChoiPublished in: Infection (2021)
Among frequently reported laboratory values, blood urea nitrogen was the most often reported predictor of mortality (91%); neutrophil-to-lymphocyte ratio was the most frequent statistically significant laboratory parameter in predicting disease severity (96%). This review highlights the temporal progression of laboratory value frequencies, as well as potentially distinct utilities of different markers for clinical outcomes of COVID-19. Future research pathways include using this collected data for focused quantitative meta-analyses of particular laboratory values correlated with clinical outcomes of mortality and disease severity.