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Gene Expression Levels of the Prolyl Hydroxylase Domain Proteins PHD1 and PHD2 but Not PHD3 Are Decreased in Primary Tumours and Correlate with Poor Prognosis of Patients with Surgically Resected Non-Small-Cell Lung Cancer.

Ana KorenMatija RijavecTomaž KrumpestarIzidor KernAleksander SadikovTanja ČuferPeter Korošec
Published in: Cancers (2021)
Our results show that reduced expression of PHD1 and PHD2 is associated with the development and progression of NSCLC. PHD1 could be further assessed as a prognostic marker in NSCLC.
Keyphrases
  • poor prognosis
  • gene expression
  • long non coding rna
  • small cell lung cancer
  • dna methylation
  • lymph node
  • binding protein