Short- vs. Long-Course Antibiotic Treatment for Acute Streptococcal Pharyngitis: Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Anna Engell HolmCarl LlorLars Bjerrum Gloria Cristina Cordoba Currea

Published in: Antibiotics (Basel, Switzerland) (2020)

Macrolides and cephalosporins belong to the list of "Highest Priority Critically Important Antimicrobials"; hence, long-course penicillin V should remain as the first line antibiotic for the management of patients with streptococcal pharyngitis as far as the benefits of using these two types of antibiotics do not outweigh the harms of their unnecessary use.

Keyphrases

systematic review
meta analyses
liver failure
respiratory failure
randomized controlled trial
drug induced
combination therapy