Widespread false gene gains caused by duplication errors in genome assemblies.

Byung June KoChul LeeJuwan KimArang RhieDong Ahn YooKerstin HoweJonathan WoodSeoae ChoSamara BrownGiulio FormentiErich D JarvisHeebal Kim

Published in: Genome biology (2022)

This study highlights the need for more advanced assembly methods that better separate haplotypes and sequence errors, and the need for cautious analyses on gene gains.

Keyphrases

genome wide
copy number
patient safety
genome wide identification
adverse drug
emergency department
dna methylation
gene expression
transcription factor
genome wide analysis