Clinical efficacy of the HIV protease-inhibitor Indinavir in combination with chemotherapy for advanced classic Kaposi's sarcoma treatment: a single-arm, phase II trial in the elderly.
Cecilia SgadariBiancamaria ScoppioOrietta PicconiAntonella TripicianoFrancesca Maria GaianiVittorio FrancavillaAngela ArancioMassimo CampagnaClelia PalladinoSonia MorettiPaolo MoniniLucia BrambillaBarbara EnsoliPublished in: Cancer research communications (2024)
In advanced CKS a strategy combining Indinavir and chemotherapy is safe and associated with high and durable response rates, and it could be rapidly adopted for the clinical management of these patients.
Keyphrases
- end stage renal disease
- newly diagnosed
- chronic kidney disease
- ejection fraction
- locally advanced
- human immunodeficiency virus
- antiretroviral therapy
- hiv infected
- hepatitis c virus
- hiv positive
- peritoneal dialysis
- hiv aids
- squamous cell carcinoma
- hiv testing
- randomized controlled trial
- middle aged
- patient reported outcomes
- open label
- community dwelling