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Scalp application of the antioxidant piroctone olamine reduces hair shedding in an 8-week randomized, double-blind, placebo-controlled clinical study.

Michael G DavisMelissa P PiliangWilma F BergfeldTamara L CaterinoBrian K FisherJarek P SachaGreg J CarrLaura T MoultonDeborah J WhittenbargerSupriya PunyaniJames R Schwartz
Published in: International journal of cosmetic science (2022)
These results illustrate the effectiveness of a cosmetic antioxidant to improve scalp condition thereby improving hair retention. The observed improvements in scalp condition are consistent with previous reports with other antioxidant technologies and suggest that the hair retention effect was achieved by preventing oxidative damage to the scalp.
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