Investigating the active chemical constituents and pharmacology of Nanocnide lobata in the treatment of burn and scald injuries.
Yanlin ZouCao YuQian HuangXiaorong TanXiaoyan TanXiaolong ZhuDongyang YiJing-Xin MaoPublished in: PloS one (2023)
Petroleum ether Nanocnide lobata extract and the volatile oil compounds of Nanocnide lobata might be effective drugs in the treatment of burn and scald injuries, as they exhibited a protective effect on burns and scalds by reducing the expression of TNF-α, IL-10 and TGF-β1 and increasing the expression of VEGF. In addition, these compounds may also exert pharmacological effects that promote wound tissue repair, accelerate wound healing, and reduce scar tissue proliferation, inflammation and pain.