A comparison of methods for estimating substitution rates from ancient DNA sequence data.

K Jun TongDavid A DuchêneSebastián DuchêneJemma L GeogheganSimon Y W Ho

Published in: BMC evolutionary biology (2018)

We recommend that phylogenetic studies of ancient DNA sequences should use multiple methods of inference and test for the presence of temporal signal, among-lineage rate variation, and phylo-temporal clustering in the data.

Keyphrases

single cell
circulating tumor
electronic health record
cell free
single molecule
big data
rna seq
nucleic acid
artificial intelligence
machine learning
data analysis
circulating tumor cells
amino acid