Efficacy of cenobamate for uncontrolled focal seizures: Post hoc analysis of a Phase 3, multicenter, open-label study.
Mickael R SperlingBassel Abou-KhalilSami AboumatarPerminder BhatiaVictor BitonPavel KleinGregory L KraussDavid G VosslerRobert T WechslerLouis FerrariMindy GrallWilliam E RosenfeldPublished in: Epilepsia (2021)
This post hoc analysis of a subset of patients from the long-term open-label study showed high rates of sustained 100% and ≥90% seizure reduction, with many achieving response early during titration. These findings suggest durable seizure frequency reduction with cenobamate in adults with uncontrolled focal seizures.