Emergence of Human Immunodeficiency Virus-1 Drug Resistance During the 3-Month World Health Organization-Recommended Enhanced Adherence Counseling Period in the CART-1 Cohort Study.
Jennifer Anne BrownHerbert A MbunkahThabo Ishmael LejoneIsaac RingeraMolisana CheleboiThomas KlimkaitKarin J MetznerHuldrych F GunthardNiklaus Daniel LabhardtRoger D KouyosNadine TschumiPublished in: Open forum infectious diseases (2021)
Despite high levels of resistance before EAC, we observed a slight decline in susceptibility scores after EAC. The risk of further accumulation of resistance during EAC has to be balanced against the benefit of avoiding unnecessary switches in those with spontaneous resuppression after EAC.