Potential sealing and repair of human FM defects after trauma with peptide amphiphiles and Cx43 antisense.
David W BarrettBabatunde O OkesolaEleni CostaChristopher ThrasivoulouDavid L BeckerAlvaro MataJan A DeprestAnna L DavidTina T ChowdhuryPublished in: Prenatal diagnosis (2020)
Whilst the nanoarchitecture revealed promising conditions to seal iatrogenic FM defects, the peptide amphiphiles need to be designed to maximize repair mechanisms and promote structural compliance with high mechanical tolerance that maintains tissue remodeling with Cx43 antisense for future treatment.