Gut Microbiota and Neuropsychiatric Disorders.
Reza BidakiSeyed Hossein Hekmati MoghaddamMaryam SadehPublished in: Basic and clinical neuroscience (2023)
Numerous studies in humans and animals hypothesize that gut microbiota dysbiosis is involved in the development of behavioral and neurological diseases such as depression, autism spectrum disorder, Parkinson disease, multiple sclerosis, stroke and Alzheimer's disease. Some of the most salient works so far regarding the brain-gut axis are mentioned below. The current knowledge on the impact of gut microbiota on nervous system diseases is far from being directly used for pharmacologic or nutritional advice toward restoration of normal bodily functions. It seems that a more comprehensive approach should be followed so that the individual effect of each kind of intervention on the patient's somatic or psychological status is determined. Future research must address global need for regimens which could reestablish normal composition of gut microorganisms after each neuropsychological disorder.
Keyphrases
- parkinson disease
- autism spectrum disorder
- multiple sclerosis
- deep brain stimulation
- white matter
- healthcare
- randomized controlled trial
- cerebral ischemia
- cognitive decline
- depressive symptoms
- sleep quality
- resting state
- gene expression
- attention deficit hyperactivity disorder
- mild cognitive impairment
- case report
- copy number
- functional connectivity
- intellectual disability
- brain injury
- blood brain barrier
- subarachnoid hemorrhage