Functional Analysis of MET Exon 14 Skipping Alteration in Cancer Invasion and Metastatic Dissemination.

Feng WangYang LiuWanglong QiuElaine ShumMonica FengDejian Zhao Deyou ZhengAlain BorczukHaiying ChengBalazs Halmos

Published in: Cancer research (2022)

These findings reveal the mechanistic function of METΔ14Ex alteration in driving metastasis and define novel metastasis-related pathways that could be targeted for more effective treatment of lung cancer with METΔ14Ex alterations.

Keyphrases

tyrosine kinase
papillary thyroid
squamous cell carcinoma
small cell lung cancer
cell migration
single cell
cancer therapy
combination therapy
gene expression
young adults