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Biomolecular Condensation: A New Phase in Cancer Research.

Anupam K ChakravartyDaniel J McGrailThomas M LozanoskiBrandon S DunnDavid J H ShihKara M CirilloSueda H CetinkayaWenjin Jim ZhengGordon B MillsS Stephen YiDaniel F JaroszNidhi Sahni
Published in: Cancer discovery (2022)
One of the fundamental functions of phase separation is to rapidly and dynamically respond to environmental perturbations. Importantly, these changes often lead to alterations in cancer-relevant pathways and processes. This review covers recent advances in the field, including emerging principles and mechanisms of phase separation in cancer.
Keyphrases
  • papillary thyroid
  • squamous cell
  • lymph node metastasis
  • squamous cell carcinoma
  • childhood cancer
  • risk assessment
  • life cycle