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Nanocarrier functionalization strategies for targeted drug delivery in skin cancer therapy: Current progress and upcoming challenges.

Leonardo Delello Di FilippoMariana Carlomagno de PaulaJonatas Lobato DuarteGeanne Aparecida de PaulaIsadora FrigieriMarlus Chorilli
Published in: Expert opinion on drug delivery (2023)
There are still several challenges that need to be addressed before the clinical translation of targeted nanoparticles, such as optimization of their properties, development of reliable and robust characterization methods, and evaluation of their safety and efficacy in clinical trials. Another key aspect for the advancement of these studies is the need to improve regulatory aspects related to the toxicity and regulation of nanomedicines targeting skin cancer. Overall, targeted nanocarriers hold great potential for the development of safe and effective treatments for skin cancer, which can contribute to a better prognosis and overall patients' life quality.
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