Prevalence, risk factors and echocardiographic predictors of pulmonary hypertension in systemic lupus erythematosus: towards a screening protocol.
Jorge Álvarez TroncosoClara Soto AbánadesÁngel Robles-MarhuendaSergio Alcolea BatresMaría Fernández Velilla PeñaSantiago Jiménez ValeroRaquel Sorriguieta TorreJuan José Rios-BlancoPublished in: RMD open (2024)
In our cohort, 7.96% of patients with SLE had an intermediate or high PH probability. By RHC, six patients (2.99%) met the ESC/European Respiratory Society criteria for PH and four (1.99%) for PAH. The main risk factors were older age, cardiorespiratory symptoms, serositis, anti-Ro, cardiac biomarkers and altered PFTs. PH was a severe SLE complication, suggesting the need for earlier diagnosis through data-driven screening to reduce associated morbidity and mortality.
Keyphrases
- risk factors
- pulmonary hypertension
- systemic lupus erythematosus
- ejection fraction
- end stage renal disease
- left ventricular
- chronic kidney disease
- newly diagnosed
- disease activity
- randomized controlled trial
- pulmonary arterial hypertension
- mitral valve
- body composition
- tyrosine kinase
- coronary artery
- middle aged
- rheumatoid arthritis
- patient reported outcomes
- depressive symptoms
- polycyclic aromatic hydrocarbons