DNA double-strand breaks repair inhibitors potentiates the combined effect of VP-16 and CDDP in human colorectal adenocarcinoma (LoVo) cells.
Paulina KopaAnna MaciejaElzbieta PastwaIreneusz MajsterekTomasz PoplawskiPublished in: Molecular biology reports (2021)
Our data support the hypothesis that NHEJ inhibitors could be used in conjunction with standard therapy to provide effective clinical improvement and allow reduction in drug doses.
Keyphrases
- induced apoptosis
- endothelial cells
- cell cycle arrest
- squamous cell carcinoma
- electronic health record
- circulating tumor
- cell free
- big data
- stem cells
- endoplasmic reticulum stress
- oxidative stress
- emergency department
- pluripotent stem cells
- machine learning
- signaling pathway
- cell death
- adverse drug
- radiation therapy
- drug induced
- artificial intelligence
- data analysis
- smoking cessation