Tauroursodeoxycholic Acid Protects Retinal and Visual Function in a Mouse Model of Type 1 Diabetes.

Jieming FuMoe H AungMegan C PruntyAdam M HanifLauren M HutsonJeffrey H Boatright Machelle T Pardue

Published in: Pharmaceutics (2021)

Early TUDCA treatment preserved visual function in an STZ-mouse model of Type I diabetes. These data add to a growing body of preclinical research that may support testing whether TUDCA may be an effective early clinical intervention against declining visual function caused by diabetic retinopathy.

Keyphrases

diabetic retinopathy
mouse model
optical coherence tomography
randomized controlled trial
type diabetes
stem cells
machine learning
mesenchymal stem cells
bone marrow
artificial intelligence