Regenerative treatments for scleroderma in cutaneous manifestations of the face: a systematic review.

Jan Aart M SchipperLisette Laura VerhoefRutger H SchepersPieter U DijkstraAlja J StelSjoukje van der WerfDouwe J MulderMartin C HarmsenJohan Jansma

Published in: Clinical and experimental rheumatology (2024)

Autologous regenerative treatments hold potential for alleviating cutaneous manifestations of the face in scleroderma. Further clinical trials should be well-designed to improve the quality of clinical evidence.

Keyphrases

cell therapy
stem cells
systemic sclerosis
mesenchymal stem cells
clinical trial
interstitial lung disease
tissue engineering
bone marrow
randomized controlled trial
risk assessment
open label
phase iii