Visible-Light-Driven, Radical-Triggered Tandem Cyclization of o-Hydroxyaryl Enaminones: Facile Access to 3-CF2 /CF3-Containing Chromones.

Haoyue XiangQinglan ZhaoZhenyu TangJunan XiaoPengju XiaChaoming WangChunhao YangXiaoqing ChenHao-Yue Xiang

Published in: Organic letters (2016)

A practical and straightforward synthetic route to construct a variety of 3-CF2/CF3-containing chromones via photoredox catalysis was developed. This novel protocol features a visible-light-induced radical-triggered tandem cyclization.

Keyphrases

visible light
cystic fibrosis
randomized controlled trial
gold nanoparticles