The influence of comorbidities on achieving an N-terminal pro-b-type natriuretic peptide target: a secondary analysis of the GUIDE-IT trial.
Justin A EzekowitzWendimagegn AlemayehuSarah RathwellAndrew D GrantMona FiuzatDavid J WhellanTariq AhmadKirkwood AdamsIliana L PiñaLawton S CooperJames L JanuzziEric S LeiferDaniel B MarkChristopher M O'ConnorG Michael FelkerPublished in: ESC heart failure (2021)
Patients with AF, a lower BMI, or worse renal function are less likely to achieve a lower or target NT-proBNP. Clinicians should be aware of these factors both when interpreting NT-proBNP levels and making therapeutic decisions about heart failure therapies.