Unraveling the therapeutic efficacy of resveratrol in Alzheimer's disease: an umbrella review of systematic evidence.
Ali AzargoonjahromiFatemeh AbutalebianPublished in: Nutrition & metabolism (2024)
RV exhibits promising potential for benefiting individuals with AD through various mechanisms. It has been observed to enhance cognitive function, reduce Aβ accumulation, provide neuroprotection, protect the BBB, support mitochondrial function, facilitate synaptic plasticity, stabilize tau proteins, mitigate oxidative stress, and reduce neuroinflammation commonly associated with AD.
Keyphrases
- oxidative stress
- cerebral ischemia
- mycobacterium tuberculosis
- blood brain barrier
- traumatic brain injury
- dna damage
- brain injury
- cognitive decline
- lipopolysaccharide induced
- lps induced
- diabetic rats
- randomized controlled trial
- induced apoptosis
- subarachnoid hemorrhage
- human health
- inflammatory response
- mild cognitive impairment
- heat shock
- heat shock protein