Specific Subtypes of Carcinoma-Associated Fibroblasts Are Correlated with Worse Survival in Resectable Pancreatic Ductal Adenocarcinoma.
Karl KnipperAlexander I DamanakisYue ZhaoChristiane J BrunsThomas SchmidtFelix C PoppAlexander QuaasSu Ir Lyunull nullPublished in: Cancers (2023)
This project identified three subgroups of PDAC with different expression patterns of CAF markers which showed significantly worse survival. This could be the base for the further characterization of the fibroblast subgroups in PDAC and contribute to the development of new targeted therapy options against CAFs.