Single-Nucleus RNA Sequencing Unravels Early Mechanisms of Human Becker Muscular Dystrophy.

Zhihao Xie Chang LiuChengyue SunYilin LiuJieru PengLingchao MengJianwen DengZhaoxia WangChunxia YangYun Yuan Zhiying Xie

Published in: Annals of neurology (2024)

Our results provide insights into the transcriptional diversity of human BMD muscle at a single-nucleus resolution and new potential targets for anti-fibrosis therapies in BMD. ANN NEUROL 2024.

Keyphrases

muscular dystrophy
endothelial cells
induced pluripotent stem cells
pluripotent stem cells
duchenne muscular dystrophy
gene expression
single cell
transcription factor
oxidative stress
neural network
heat shock