Spermatogenesis associated serine rich 2 like plays a prognostic factor and therapeutic target in acute myeloid leukemia by regulating the JAK2/STAT3/STAT5 axis.
Fenglin LiWenle YeYiyi YaoWenwen WeiXiangjie LinHaihui ZhuangChenying LiXia LiQing LingChao HuXin HuangYu QianShihui MaoJiansong HuangYing LuJie JinPublished in: Journal of translational medicine (2023)
High expression of SPATS2L is a poor prognostic factor in AML, and targeting SPATS2L may be a promising therapeutic strategy for AML patients.
Keyphrases
- prognostic factors
- acute myeloid leukemia
- poor prognosis
- end stage renal disease
- cell proliferation
- allogeneic hematopoietic stem cell transplantation
- chronic kidney disease
- ejection fraction
- acute lymphoblastic leukemia
- newly diagnosed
- long non coding rna
- binding protein
- peritoneal dialysis
- protein kinase
- patient reported