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Hepatic stem cells with self-renewal and liver repopulation potential are harbored in CDCP1-positive subpopulations of human fetal liver cells.

Ran-Ran ZhangYun-Wen ZhengBin LiYun-Zhong NieYasuharu UenoTomonori TsuchidaHideki Taniguchi
Published in: Stem cell research & therapy (2018)
We identified a human hepatic stem/progenitor population in the CDCP1+CD90+CD66- subpopulation in human FLCs, indicating CDCP1 marker could potentially be utilized to identify and isolate HpSCs for further cytotherapy of liver disease.
Keyphrases
  • endothelial cells
  • stem cells
  • pluripotent stem cells
  • cell therapy
  • endoplasmic reticulum stress