Assessment of brain age in posttraumatic stress disorder: Findings from the ENIGMA PTSD and brain age working groups.
Ashley N ClausenKelene A FerchoMolly MonsourSeth DisnerLauren SalminenCourtney C HaswellEmily Clarke RubrightAmanda A WattsM Nicole BuckleyAdi Maron-KatzAnika SierkAntje MantheyBenjamin Suarez-JimenezBunmi O OlatunjiChristopher L AverillDavid HofmannDick J VeltmanElizabeth A OlsonGen LiGina L ForsterHenrik WalterJacklynn M FitzgeraldJean ThébergeJeffrey S SimonsJessica A BomyeaJessie L FrijlingJohn H KrystalJustin T BakerK Luan PhanKerry ResslerLaura K M HanLaura NawjinLauren A M LeboisLianne SchmaalMaria DensmoreMartha E ShentonMirjam van ZuidenMurray SteinNegar FaniRaluca M SimonsRichard W J NeufeldRuth A LaniusSanne J H van RooijSaskia B J KochSerena BonomoRebecca HinrichsTerri deRoon-CassiniTimothy D ElyVincent A MagnottaXiaofu HeChadi G AbdallahAmit EtkinChristian SchmahlChristine LarsonIsabelle M RossoJennifer Urbano BlackfordJennifer S StevensJudith K DanielsJulia HerzogMilissa L KaufmanMiranda OlffRichard J DavidsonScott R SponheimSven C MuellerThomas StraubeXi ZhuYuval NeriaLee A BaughJames H ColePaul M ThompsonRajendra A MoreyPublished in: Brain and behavior (2021)
Differential impact of PTSD on brain PAD in younger versus older males may indicate a critical window when PTSD impacts brain aging, followed by age-related brain changes that are consonant with individuals without PTSD. Future longitudinal research is warranted to understand how PTSD impacts brain aging across the lifespan.