GNAO1 Mutations Affecting the N-Terminal α-Helix of Gαo Lead to Parkinsonism.
Gonzalo P SolisYonika Arum LarasatiMoritz ThielAlexey KovalAnne KoyVladimir L KatanaevPublished in: Movement disorders : official journal of the Movement Disorder Society (2024)
Our study defines a parkinsonism phenotype within the spectrum of GNAO1 disorders and suggests a genotype-phenotype correlation by GNAO1 mutations targeting the N-terminal α-helix of Gαo. © 2024 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.