Genomic characterization of SARS-CoV-2 from vaccine breakthrough cases in Allegheny County, Pennsylvania.

Kady D WaggleMarissa P GriffithLei ZhuVaughn S CooperDaniel J SnyderVatsala SrinivasaTung PhanAlan WellsGraham M SnyderDaria Van TyneLee H HarrisonJane W Marsh

Published in: PloS one (2022)

We performed whole genome sequencing on SARS-CoV-2 from 59 vaccinated individuals from southwest Pennsylvania who tested positive between February and September, 2021. A comparison of mutations among vaccine breakthrough cases to a time-matched control group identified potential adaptive responses of SARS-CoV-2 to vaccination.

Keyphrases

sars cov
respiratory syndrome coronavirus
gene expression
dna methylation
coronavirus disease
human health
genome wide