ADAMTS1 and HSPG2 mRNA levels in cumulus cells are related to human oocyte quality and controlled ovarian hyperstimulation outcomes.
Yerong MaJiamin JinXiaomei TongWeijie YangPeipei RenYongdong DaiYibin PanYinLi ZhangSong-Ying ZhangPublished in: Journal of assisted reproduction and genetics (2020)
The dynamic profiles of ADAMTS1 and HSPG2 were inversely correlated in CCs. In PCOS and normal ovulatory patients, higher ADAMTS1 and lower HSPG2 expression levels in CCs were related to better COH outcomes.
Keyphrases
- end stage renal disease
- newly diagnosed
- induced apoptosis
- chronic kidney disease
- ejection fraction
- poor prognosis
- prognostic factors
- binding protein
- type diabetes
- metabolic syndrome
- polycystic ovary syndrome
- cell proliferation
- oxidative stress
- patient reported outcomes
- quality improvement
- adipose tissue
- patient reported
- weight loss
- cell death