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Secreted Protein Profiling of Human Aortic Smooth Muscle Cells Identifies Vascular Disease Associations.

Rédouane AherrahrouFerheen BaigKonstantinos TheofilatosDillon LueAlicia BeeleTiit ÖrdMinna U KaikkonenZouhair AherrahrouQi ChengSaikat Kumar B GhoshSantosh KarnewarVaishnavi KarnewarAloke V FinnGary K OwensMichael JonerManuel MayrMete Civelek
Published in: Arteriosclerosis, thrombosis, and vascular biology (2024)
Our results unravel the SMC proteome signature associated with vascular disorders, which may help identify potential therapeutic targets to accelerate the pathway to translation.
Keyphrases
  • endothelial cells
  • aortic valve
  • left ventricular
  • induced pluripotent stem cells
  • pluripotent stem cells
  • protein protein
  • heart failure
  • small molecule
  • genome wide analysis