Quadruple therapies show a higher eradication rate compared to standard triple therapy for Helicobacter pylori infection within the LEGACy consortium. A multicenter observational study in European and Latin American countries.
Patricio Medel-JaraDiego Reyes PlacenciaEduardo Fuentes-LópezOscar CorsiGonzalo LatorreRosario AntónElena JiménezAna Miralles-MarcoCarmelo CaballeroHugo BogginoDaniel CanteroRita BarrosJoão Santos-AntunesMarc DíezLuis A QuiñonesErick RiquelmeAntonio RollánLeslie C CerpaIvania ValdésOlga P NyssenLeticia MoreiraJavier P GisbertM Constanza CamargoNayeli Ortiz-OlveraAlberto M Leon-TakahashiErika Ruiz-GarciaEdith A Fernández-FigueroaMarcelo GarridoGareth I OwenAndrés CervantesTania C FleitasArnoldo Riquelme PérezPublished in: United European gastroenterology journal (2024)
Both QCT and QBT are superior to STT for H. pylori eradication when adjusted for country-specific antibiotic resistance and CYP2C19 polymorphism in a sample of individuals residing in five countries within two continents.