Validation of the ACE (Albumin, CRP and Endoscopy) Index in Acute Colitis: Analysis of the CONSTRUCT dataset.

Rebecca K GrantGareth-Rhys JonesNikolas PlevrisRuairi W LynchWilliam M BrindleHayley Anne HutchingsJohn G WilliamsLaith AlrubaiyAlan WatkinsCharlie W LeesIan D R Arnott

Published in: Journal of Crohn's & colitis (2023)

We have now reported and externally validated the ACE Index in Acute Colitis in a combined cohort of over 1000 patients from across the United Kingdom. The ACE Index may be used in conjunction with clinical judgement to help identify patients admitted with active UC who are at high risk of not responding to IV steroids. Further studies are required to improve objectivity and accuracy of assessment.

Keyphrases

liver failure
angiotensin converting enzyme
angiotensin ii
end stage renal disease
respiratory failure
newly diagnosed
ejection fraction
drug induced
chronic kidney disease
ulcerative colitis
cross sectional
extracorporeal membrane oxygenation
small bowel
acute respiratory distress syndrome