Comparison of the efficacy of electroconvulsive therapy (ECT) plus agomelatine to ECT plus placebo in treatment-resistant depression.

Ching-Hua LinW-C YangC-C ChenW-R Cai

Published in: Acta psychiatrica Scandinavica (2020)

Adding agomelatine to ECT yielded comparable response/remission rates to ECT without agomelatine in the acute ECT phase. Starting agomelatine in combination with ECT did not seem to be more efficacious in preventing relapse than starting agomelatine after the acute ECT course. More research is needed to guide clinical recommendations.

Keyphrases

liver failure
respiratory failure
drug induced

randomized controlled trial
rheumatoid arthritis
intensive care unit

aortic dissection
physical activity
mechanical ventilation

free survival
clinical evaluation