Physical Activity and Nutrition: Two Promising Strategies for Telomere Maintenance?
Estelle BalanAnabelle DecottigniesLouise DeldicquePublished in: Nutrients (2018)
As the world demographic structure is getting older, highlighting strategies to counteract age-related diseases is a major public health concern. Telomeres are nucleoprotein structures that serve as guardians of genome stability by ensuring protection against both cell death and senescence. A hallmark of biological aging, telomere health is determined throughout the lifespan by a combination of both genetic and non-genetic influences. This review summarizes data from recently published studies looking at the effect of lifestyle variables such as nutrition and physical activity on telomere dynamics.
Keyphrases
- physical activity
- public health
- cell death
- genome wide
- body mass index
- healthcare
- copy number
- mental health
- electronic health record
- sleep quality
- high resolution
- dna methylation
- endothelial cells
- type diabetes
- global health
- big data
- machine learning
- health information
- risk assessment
- systematic review
- gene expression
- signaling pathway
- mass spectrometry
- climate change
- case control
- weight loss
- social media