Synovial tissue biopsy analysis: unlocking the hidden secrets to personalised medicine?
Helen Michelle McGettrickPublished in: Arthritis research & therapy (2019)
Rheumatoid arthritis is an immune-mediated inflammatory disease of the synovium. Yet we still lack robust tissue-specific (synovial) biomarkers that are able to guide clinical decisions and stratify patients according to their disease subgroup and predicted response to treatment. The EULAR Synovitis Study Group and the OMERACT synovial tissue biopsy (STB) Special Interests Group have undertaken a consensus exercise to identify factors that are important for the standardisation of STB handling and analytical procedures in two situations-clinical practice and translational research.
Keyphrases
- clinical practice
- rheumatoid arthritis
- end stage renal disease
- chronic kidney disease
- newly diagnosed
- ultrasound guided
- ejection fraction
- physical activity
- oxidative stress
- high intensity
- fine needle aspiration
- peritoneal dialysis
- disease activity
- randomized controlled trial
- mass spectrometry
- liquid chromatography
- systemic sclerosis
- idiopathic pulmonary fibrosis
- study protocol
- data analysis