Transition of the programmed death 1 pathway from the primary colorectal cancer to its corresponding pulmonary metastasis.
Ei MiyamotoToyofumi F Chen-YoshikawaChiyuki UeshimaAkihiko YoshizawaMasatsugu HamajiTakamasa YamamotoKenji KawadaHironori HagaYoshiharu SakaiHiroshi DatePublished in: Journal of surgical oncology (2018)
The discordance of PD-L1 expression between the primary tumor and its PM was found in one-third of our patients with CRC. Temporally distant PM from CRC could be associated with the positive expression of PD-L1 in the PM.